ACTIVASE rt-PA alteplase 100mg powder for solution for injection (Canada)

ACTIVASE rt-PA (alteplase for injection) is indicated for:

• The lysis of suspected occlusive coronary artery thrombi associated with evolving transmural myocardial infarction. Treatment should be initiated as soon as possible after the onset of acute myocardial symptoms.
• The management of acute ischemic stroke (AIS) in adults for improving neurological recovery and reducing the incidence of disability. Treatment should only be initiated within 3 hours after the onset of stroke symptoms, and after exclusion of intracranial hemorrhage by a cranial computerized tomography (CT) scan or other diagnostic imaging method sensitive for the presence of hemorrhage.