(Approval lapsed) Atropine Sulphate 1mg/5mL solution for injection pre-filled syringe (Aguettant, UK)

Atropine sulfate 0.2 mg/mL, solution for injection in pre-filled syringe is indicated in adults only.

Cardiac:

• In the management of patients with severe bradycardia and bradyarrhythmias to increase the heart rate.
• Patients with Type I atrioventricular conduction deficits to lessen the degree of atrioventricular heart block.

Anaesthesia:

• Atropine is indicated as an antisialogogue in anaesthetic premedication to reduce or prevent secretions in the respiratory tract.
• During anaesthesia, atropine may be used to prevent reflex bradycardia and restore cardiac rate and arterial pressure resulting from the increased vagal activity associated with laryngoscopy, tracheal intubation and intra-abdominal manipulation, and for the prevention of the oculo-cardiac reflex during ophthalmic surgery. It may also be used to block muscarinic effects when neostigmine is used to counter the action of muscle relaxants.

Anticholinesterase poisoning: