(Approval lapsed) Estradiol Transdermal System 75mcg/day (0.075mg/day) (Sandoz, USA)

Short term treatment of symptoms of estrogen deficiency due to the menopause, whether natural or surgically induced. In women with an intact uterus, estrogen should always be opposed by progestogen in an adequate dosage regimen to ensure secretory transformation of the endometrium at regular intervals. Combination HRT should not be used in hysterectomised women because it is not needed in these women and it may increase the risk of breast cancer.