You are here Home Safety review of diclofenac Version 2.1, October 2014 Last updated 7 October 2014 Listen Print Share LinkedIn (Twitter) Facebook Email Loading... Following the cardiovascular safety review of all NSAIDs and concerns regarding the risk of hepatotoxicity, the Office of Product Review (OPR) conducted a full safety review of diclofenac. Supporting documents Safety review of diclofenac [PDF, 681.65 KB] Safety review of diclofenac [Word, 269.87 KB] Topics Medicines safety